Effectiveness of using Emdogain® in periodontal tissue regeneration
Keywords:
Enamel matrix derivatives, Emdogain, Periodontal Guided Tissue Regeneration, Bone Loss, Periodontal diseaseAbstract
Introduction: complications of periodontitis include intrabony defects and lesions in periodontal tissues, the lack of which can result in tooth loss. Therefore, regenerative periodontal therapy is used, where a therapeutic alternative is the use of proteins derived from the enamel matrix such as Emdogain®. Objective: describe the effectiveness of the enamel matrix derivative in periodontal regeneration Emdogain®. Method: bibliographic review was carried out in various digital data sources such as Science Direct, PubMed, Elsevier, Scielo and Proquest. Qualitative, quantitative, comparative and correlational studies, case studies and clinical trials performed on humans were included; keywords were used for the search. Results: the use of Emdogain® for a minimum period of six months helps to reduce the separation between the gingival margin and the base of the periodontal pocket. Its use is more effective when combined with scaling and root planing, favoring the recovery of the vertical clinical attachment level or the reference measurement that exists between the filaments of the gingival connective tissue and the root cementum. Conclusions: it was determined that the application of Emdogain®, in surgical and non-surgical periodontal therapy, is effective in periodontal tissue regeneration. Its clinical protocol is recommended in the therapy of intrabony defects and decreased probing depth. Emdogain® in periodontal treatment is effective in the regeneration of periodontal defects, since it mainly improves probing depth and the vertical clinical attachment level.
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