Role of microorganisms in intestinal autofermentation syndrome
Keywords:
alcoholic self-distillation syndrome, ethanol, diagnosis, Endogenous alcohol fermentationAbstract
Introduction: Oncolytic virotherapy has been established as a emerging therapeutic tactic in cancer immunotherapy, employing genetically altered viruses to treat only malignant cells without harming healthy tissue. Objective: identify the oral microorganisms involved in the development of ASD. Method: a literature review was conducted using scientific articles, case reports, and a case-control study, ensuring publication within the 2018-2024 time frame. Development: the main treatment for ASD focuses on the use of antifungals, with oral fluconazole 100-150 mg for 14 days usually being the first choice. However, due to resistance to fluconazole, nystatin 50,000 IU was administered together three times for 10 days. Additionally, the alternative is the use of micafungin 150 mg IV in cases where oral therapy does not work. Conclusions: this study has revealed the relationship between oral microorganisms and AAS, corroborated by several case reports that have confirmed the decisive influence of these agents in the pathogenesis of the syndrome. Notably, Saccharomyces cerevisiae has been documented to emerge most frequently as the predominant microorganism.
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