Relationship between vitiligo and covid-19
Keywords:
vitiligo, SARS-CoV-2, skin manifestations, stains, interleukin-6Abstract
Introduction: The pandemic caused by the SARS-Cov2 respiratory virus generated a significant global crisis due to its high mortality and morbidity rate. In recent years there have been cases of people who have developed skin manifestations such as vitiligo either during the disease or after vaccination. Objective: describe the relationship between Vitiligo and Covid-19 in order to facilitate its diagnosis and treatment. Method: a bibliographic review was carried out where the analysis of original articles and updated systemic reviews that provided us with information about vitiligo and SARS-Cov2 was carried out. The search was carried out in bibliographic search engines such as Clinical Key, Pubmed, Google Scholar, taking into account the most relevant articles within the scientific community. Keywords such as “Vitiligo” and “Vitiligo associated with COVID-19” were taken into account for the search. Result: in the studies and articles analyzed, the appearance of some autoimmune diseases is evident, in which vitiligo stands out. Stress due to COVID-19 and the spread of vitiligo are associated. Stress and stressors can have a profound effect on autoimmunity, with vitiligo being an autoimmune disease. Conclusion: the pathogenesis of vitiligo is complex and involves the interaction of multiple factors, including oxidative stress and autoimmunity with genetic susceptibility. COVID-19 disease triggers a cytokine storm, in which an elevation of IL-6 is observed, while vitiligo can probably increase the cytokine cascade and worsen the prognosis. Key words: vitiligo; SARS-CoV-2; skin manifestations; stains; interleukin-6
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